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#health Evaluation of betamethasone dipropionate therapeutic level in GCF: Development of RP-HPLC method for determination of betamethasone dipropionate in gingival crevicular fluid

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Evaluation of betamethasone dipropionate therapeutic level in GCF: Development of RP-HPLC method for determination of betamethasone dipropionate in gingival crevicular fluid

Periodontal disease is one of the most frequently encountered chronic inflammatory disease of the oral cavity. Current research data imply that the pathogenesis of periodontal disease is mediated by the host response giving the rationale for the usage of locally applied corticosteroids, such as betamethasone dipropionate (BDP), in periodontal therapy. Gingival crevicular fluid (GCF), an inflammatory exudate formed during the course of periodontal disease, is a valuable matrix for therapeutic mon

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